Read e-book online Alcohol and the Nervous System PDF

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By Edith V. Sullivan, Adolf Pfefferbaum

ISBN-10: 0444626190

ISBN-13: 9780444626196

Alcohol is the main wide-spread drug on this planet, but alcoholism continues to be a significant habit affecting approximately 20 million american citizens. Our present realizing of alcohol's impact on mind constitution and similar practical harm is being revolutionized by way of genetic learn, uncomplicated neuroscience, mind imaging technology, and systematic research of cognitive, sensory, and motor skills. quantity a hundred twenty five of the instruction manual of medical Neurology is a accomplished, in-depth treatise of reports on alcohol and the mind protecting the elemental knowing of alcohol's impact at the imperative fearful approach, the analysis and remedy of alcoholism, and prospect for restoration. The chapters inside should be of curiosity to scientific neurologists, neuropsychologists, and researchers in all features and degrees of the neuroscience of alcohol and alcoholism.

  • The first targeted reference particularly on alcohol and the brain
  • Details our present realizing of ways alcohol affects the crucial fearful system
  • Covers medical and social influence of alcohol abuse problems and the biomedical effects of alcohol abuse
  • Includes part on neuroimaging of neurochemical markers and mind function

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Extra info for Alcohol and the Nervous System

Example text

J Neurosci 28: 3729–3737. Pfefferbaum A, Sullivan EV, Mathalon DH et al. (1997). Frontal lobe volume loss observed with magnetic resonance imaging in older chronic alcoholics. Alcohol Clin Exp Res 21: 521–529. Pitel AL, Chanraud S, Muller-Oehring EM et al. (2013). Modulation of limbic-cerebellar functional connectivity enables alcoholics to recognize who is who. Brain Struct Funct 218: 683–695. Powell BJ, Campbell JL, Landon JF et al. (1995). A doubleblind, placebo-controlled study of nortriptyline and bromocriptine in male alcoholics subtyped by comorbid psychiatric disorders.

1997). Quantitative trait loci involved in genetic predisposition to acute alcohol withdrawal in mice. J Neurosci 17: 3946–3955. Buck KJ, Milner LC, Denmark DL et al. (2012). Discovering genes involved in alcohol dependence and other alcohol responses: role of animal models. Alcohol Res 34: 367–374. T. REILLY ET AL. Camchong J, Stenger A, Fein G (2013a). Resting-state synchrony during early alcohol abstinence can predict subsequent relapse. Cereb Cortex 23: 2086–2099. Camchong J, Stenger A, Fein G (2013b).

The remainder of this review explores the neuroadaptational changes that occur in the brain emotional systems to account for the neurocircuitry changes that produce opponent processes and are hypothesized to play a key role in the compulsivity of addiction. NEUROCIRCUITS FOR THE BINGE/ INTOXICATION STAGE ASSOCIATED WITH ALCOHOLISM Animal models for the acute reinforcing effects of alcohol and the use of selective antagonists for specific neurochemical systems have supported the hypothesis that alcohol at intoxicating doses has a wide but selective action on neurotransmitter systems in the brain reward systems.

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Alcohol and the Nervous System by Edith V. Sullivan, Adolf Pfefferbaum

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