A Skeptic's Guide to the Mind: What Neuroscience Can and - download pdf or read online

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By Robert Burton

ISBN-10: 125002840X

ISBN-13: 9781250028402

What if our soundest, most logical judgments are past our control?

Despite 2500 years of contemplation via the world's maximum minds and the more moderen extraordinary advances in easy neuroscience, neither neuroscientists nor philosophers have a good realizing of what the brain is or the way it works. the space among what the mind does and the brain reviews is still uncharted territory. however, with robust new instruments comparable to the fMRI test, neuroscience has develop into the de facto mode of rationalization of habit. Neuroscientists let us know why we favor Coke to Pepsi, and the media trumpets headlines comparable to "Possible web site of unfastened will present in brain." Or: "Bad habit all the way down to genes, now not negative parenting."

Robert Burton believes that whereas a few neuroscience observations are actual advances, others are overreaching, unwarranted, wrong-headed, self-serving, or simply undeniable ridiculous, and infrequently with the opportunity of catastrophic own and social results. In A Skeptic's advisor to the Mind, he brings jointly scientific observations, useful proposal experiments, own anecdotes, and state-of-the-art neuroscience to decipher what neuroscience can let us know – and the place it falls woefully brief. whilst, he deals a brand new imaginative and prescient of ways to consider what the brain could be and the way it really works.
A Skeptic's consultant to the Mind is a severe, startling, and expansive trip into the mysteries of the mind and what makes us human.

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Extra info for A Skeptic's Guide to the Mind: What Neuroscience Can and Cannot Tell Us About Ourselves

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Ii) Upregulation/Supersensitivity of D1 Receptors In contrast to acute administration, chronic administration of psychostimulants lowers the extracellular level of DA in the PFC (Castner et al. 2005; Pierce and Kalivas 1997). This induces sensitization. In patients with schizophrenia, using [11C]NNC 112 as a radiotracer, Abi-Dargham et al. (2002) reported an increase in the binding potential of D1 receptors. However, the study by Okubo et al. (1997), which used [11C]SCH 23390, showed reduced binding of D1 receptors in the PFC.

PMID: 10518181. Ando N, Morimoto K, Watanabe T, Ninomiya T and Suwaki H (2004) Enhancement of central dopaminergic activity in the kainate model of temporal lobe epilepsy: implication for the mechanism of epileptic psychosis. Neuropsychopharmacology 29(7):1251-1258. PMID: 15039765. Andreasen NC, Rezai K, Alliger R, Swayze VW 2nd, Flaum M, Kirchner P, Cohen G, O'Leary DS (1992) Hypofrontality in neuroleptic-naive patients and in patients with chronic schizophrenia. Assessment with xenon 133 single-photon emission computed tomography and the Tower of London.

Under the hyperdopaminergic condition, in contrast, the prefrontal cortical circuit is stable, exerting negative feedback to control the dopamine release in the prefrontal cortex. Even in this case, however, a decrease in GABAergic inhibition can make the circuit unstable, causing hyperactivity of the PFC, as we will see below. PFC ACTIVITY WITH WIDE VARIATION OF D1 RECEPTOR ACTIVATION Mode Diagram To the author’s knowledge, the circuit dynamics of the PFC beyond the inverted-U region has never been argued.

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A Skeptic's Guide to the Mind: What Neuroscience Can and Cannot Tell Us About Ourselves by Robert Burton

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